Autotransplantation of teeth with incomplete root formation: systematic review and meta-analysis.

OBJECTIVES: To determine the survival of intentional autotransplantation of developing teeth. MATERIAL AND METHODS: An electronic search was carried out in the MEDLINE database, Web of Science, and Cochrane Library. The criteria used are the ones described in the PRISMA Declaration. The following MeSH terms were used: ("tooth" [MeSH Terms] OR "tooth" [All Fields]) AND ("transplantation, autologous" [MeSH Terms] OR ("transplantation" [All Fields] AND "autologous" [All Fields]) OR "autologous transplantation" [All Fields] OR "autotransplantation" [All Fields]) AND ("humans" [MeSH Terms]. Randomised clinical trials and prospective and retrospective clinical studies were included. RESULTS: The meta-analytic study of overall survival included a total of 14 studies, yielding an overall survival rate of 97.9%. In studies with 1-year follow-ups, survival was 98%. The resulting 2-year follow-up rate was 97%, while the 5- and 10-year survival rates were 95.9% and 96.9%, respectively. CONCLUSIONS: The autotransplantation technique performed in a single-phase and on teeth that have not completed their development is a predictable technique, with a described survival rate at a 2-year follow-up of more than 97%. CLINICAL RELEVANCE: The technique of dental autotransplantation is considered an important resource for the resolution and rehabilitation of tooth loss in patients, especially in those who are still in a growth period. Moreover, this technique has a low complication rate and a 10-year survival rate of 96.9%. It should therefore be considered a safe and reliable procedure.

Efectividad de las células madre mesenquimales en las elevaciones de seno maxilar. Revisión de la literatura / Effectiveness of mesenchymal stem cells in maxillary sinus lift. A literature review

Actualmente, la implantología está considerada como la terapia de elección para rehabilitar dientes ausentes. Sin embargo, debido a diversos factores, no siempre se consigue un enfoque inmediato para la colocación de los implantes. Se debe prestar una atención especial a los sectores maxilares posteriores, que debido al paso del tiempo y a la ausencia de dientes, sufren una gran atrofia alveolar que se encuentra asociada a una expansión del seno maxilar que dificulta, en ocasiones, la rehabilitación con implantes osteointegrados. Debido a esta pérdida ósea, se han desarrollado técnicas quirúrgicas como la elevación de seno maxilar para obtener una ganancia de hueso y poder favorecer la colocación y el pronóstico de los implantes. Sin embargo, existen situaciones en las que incluso esta técnica no aporta un volumen óseo suficiente, siendo preciso acompañarla de técnicas de regeneración ósea.En la actualidad, existen estudios que plantean el uso de células madre mesenquimales en procedimientos de regeneración ósea como alternativa a los procedimientos convencionales.El objetivo del presente trabajo es evaluar a través de la realización de una revisión sistemática de la literatura, la efectividad de las células madres mesenquimales en elevaciones de seno maxilar con diferentes tipos de matriz ósea. (AU)

Currently, implantology is considered the therapy of choice to rehabilitate missing teeth. However, due to various factors, we do not always get an immediate approach to the placement of our implants. Above all, we must pay special attention to the posterior maxillary sectors, which due to the passage of time and the absence of dental pieces suffer great alveolar atrophy associated with an expansion of the maxillary sinus that makes difficult and sometimes impossible the implant therapy. Due to this great bone loss, the professionals have been forced to practice surgical techniques such as maxillary sinus lift to gain bone and to be able to favour the placement and prognosis of the implants. However, there are clinical situations in which even this technique does not give us sufficient bone volume, being necessary a bone regeneration therapy.Thus, thanks to advances in the field of scientific research, various methods have been used to solve this type of problem, but one of the most innovative and current options is bone regeneration using mesenchymal stem cells.This work aims to evaluate, carrying out a systematic review of the literature, the effectiveness of mesenchymal stem cells in maxillary sinus elevations with several types of matrix. (AU)